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WOC 2022

Shin Hyun Hwa

Shin Hyun Hwa, Speaker at Weight Management Conferences
The Catholic University, Korea, Republic of
Title : The Association Between Hyperuricemia and Metabolic Risk Components in Korean Pre-menopausal Women



Menopause is one of the most important events in women life which changes the metabolism. While the correlation between metabolic syndrome and hyperuricemia in post-menopausal women has already been reported, the association in pre-menopausal women has not been studied. Thus, this study was designed to evaluate the association between hyperuricemia and metabolic risk components in Korean pre-menopausal women.


This study used data collected from the Korea National Health and Nutrition Examination Survey(KNHANES) 2016, which was conducted from January to December 2016. Total 2,958 (N=25,344,879) were examined among 4,305 women participants. A multiple logistic regression analysis was used to evaluate the association between hyperuricemia and metabolic risk components(by metabolic syndrome) in Korean pre-menopausal and post-menopausal women; presenting as odd-ratios (OR) with 95% confidence interval(95% CI).


Among 2,958 participants, 57.6% (n=1,508) was pre-menopausal. In pre-menopausal women, hyperuricemia was associated with abdominal obesity (OR 6.35, 95% CI 3.42-11.80, P<0.001), high blood pressure (OR 3.67, 95% CI 1.86-7.21, P<0.001), hypertriglycemia (OR 3.53, 95% CI 1.68-7.39, P=0.001), and impaired fasting glucose (OR 2.15, 95% CI 1.10-4.20, P=0.026). After adjustment (Model 3), it was significantly associated with abdominal obesity (OR 4.30, 95% CI 1.02-18.04, P=0.046), high BP (OR 3.23, 95% CI 1.53-6.85, P=0.002), and hypertriglycemia (OR 3.08, 95% CI 1.40-6.78, P=0.005). In contrast, no metabolic risk was significantly associated with hyperuricemia in post-menopausal women.


In Korean pre-menopausal group, hyperuricemia was significantly associated with abdominal obesity, high blood pressure, and hypertriglycemia.


Dr. Hyun Hwa Shin studied Medicine at the Catholic University of Korea and received her MD degree in 2013. She is working in the department of Family Medicine as a Family Medicine specialist.