Abstract:
Obesity is a significant risk factor for life-threatening diseases that increase morbidity and mortality rates. Currently, obesity is a worldwide epidemic, and the prevalence of obesity has been rising at unprecedented levels. The obesity rate among adults aged 20 and older is 40.5%, with a higher prevalence among those aged 40-59 compared to the 20-39 and 60 and older age groups (CDC, 2024). While dietary habits contribute to the rising obesity rates, genetics also play a significant role. The Melanocortin 4 Receptor (MC4R) gene is responsible for approximately 6% of obesity cases and significantly influences weight gain, particularly with the consumption of high-calorie foods. Many individuals are at a higher risk of obesity due to genetic variants associated with specific eating behaviors. Thus, identifying causal genetic variants can help understand which genes and biological mechanisms underlie food preference. Understanding the drivers of food choices may help address the escalating obesity problem. This study aims to investigate the influence of MC4R gene variants on food preferences in adults. By understanding the biological factors that drive individual food choices, we can potentially guide people toward healthier lifestyles and help reduce obesity.
Audience Take Away Notes:
- Learn about MC4R variants and their link to food intake and obesity
- Understand how a person's genetic makeup influences their dietary choices
