Abstract:
Disruptions of biological processes operating within adipose tissue can disturb healthy systemic physiology and develop metabolic diseases such as obesity and type 2 diabetes. Uncovering the biomolecular processes regulating adipocyte functionality can be the key to mitigating metabolic diseases. More than an inert depot to store triacylglycerol, adipose tissue is a dynamic and metabolically active endocrine organ, with diverse adipocyte populations that can contribute to metabolic health and disease. Different strategies can be used to prevent or reduce body weight gain and fat mass, as well as to maintain healthy adipose tissue, and lifestyle interventions should be pillars in this process. In this talk, we will explore the morphological and functional characteristics of different types of adipocytes, mechanisms triggered by physical exercise to improve adipocyte functionality and contribute to the prevention of obesity.
