Obesity has been linked to various changes in brain structure and function, particularly in regions associated with reward processing, appetite control, and impulse regulation. Research indicates that excess body weight may reduce gray matter volume in areas critical to decision-making and memory, potentially increasing susceptibility to cognitive decline. Furthermore, obesity can intensify inflammatory responses and oxidative stress in the brain, affecting neurotransmitter function and leading to issues like depression and anxiety. These changes can create a feedback loop, where individuals may rely more on food for emotional regulation, further promoting weight gain. Addressing obesity can support both physical health and cognitive resilience, emphasizing the brain-body connection in weight management.