Obesity often stems from disruptions in key hormones that regulate metabolism and appetite. Insulin, which helps control blood sugar, can become less effective in individuals with obesity, leading to insulin resistance and promoting further fat storage. Leptin, a hormone that signals fullness, may be overproduced yet ineffective due to leptin resistance, causing persistent hunger and overeating. Additionally, cortisol, known as the "stress hormone," can lead to fat accumulation, particularly around the abdomen, when chronically elevated. Managing these hormonal imbalances through lifestyle changes, stress reduction, and sometimes medication can be essential for achieving sustainable weight loss and reducing obesity-related health risks.