Homeostatic control of body weight refers to the body’s mechanisms for maintaining a stable weight despite fluctuations in food intake or energy expenditure. This regulation is primarily controlled by the hypothalamus, which processes signals related to hunger, satiety, and fat storage. Hormones like leptin, insulin, and ghrelin play key roles in these processes, influencing appetite and energy balance. In obesity, the body’s homeostatic mechanisms may become disrupted, making it difficult to lose weight or maintain weight loss. Restoring balance through behavioral changes, such as diet modifications and increased physical activity, can help improve the body's ability to regulate weight and prevent further fat accumulation.