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Fat cell turnover refers to the process by which old fat cells are replaced by new ones. In individuals with obesity, this turnover can become dysregulated, leading to an increase in fat cell numbers and size. Obese individuals often have larger fat cells, which can result in chronic fat retention. As a person gains weight, their body may produce more fat cells to accommodate excess fat, but these cells may not function efficiently, impairing fat storage and metabolism. Additionally, slower fat cell turnover can make it harder to lose weight, as the body becomes less capable of replacing damaged or excess fat cells. Understanding this mechanism is important for developing strategies to manage obesity, potentially through treatments that promote healthier fat cell turnover, which could aid in weight loss and metabolic balance.
