Obesity significantly impacts endocrine function, particularly hormones that regulate appetite, metabolism, and fat distribution. Excess body fat can lead to disruptions in hormones like leptin, ghrelin, insulin, and cortisol, all of which play roles in weight management. For instance, leptin resistance in obesity can lead to reduced satiety signals, making it difficult to control food intake. Elevated insulin levels may promote fat storage, especially in the abdominal area, while chronic stress can increase cortisol, which is associated with weight gain. Addressing obesity through lifestyle changes and dietary improvements can help rebalance endocrine function, facilitating weight loss and promoting overall hormonal health.