Appetite control is a complex process influenced by a network of hormonal and neural signals that regulate hunger and satiety. In obesity, this regulatory system can be disrupted. Key hormones like ghrelin, which stimulates appetite, and leptin, which signals fullness, often function abnormally. Individuals with obesity may experience heightened ghrelin levels and reduced sensitivity to leptin, leading to increased hunger and decreased satiety. Additionally, psychological factors, stress, and environmental cues, such as the availability of high-calorie foods, further complicate appetite regulation. Managing appetite in obesity often requires behavioral changes, hormonal therapies, and sometimes medications that target appetite pathways to help restore balance and support sustainable weight loss.