The field of bariatric medicine has introduced groundbreaking treatments to address severe obesity and related health conditions. Innovations like endoscopic sleeve gastroplasty (ESG) and intragastric balloon procedures are minimally invasive alternatives to traditional surgeries. ESG reduces stomach size through suturing, which helps decrease food intake, while intragastric balloons create a feeling of fullness without altering stomach structure permanently. Additionally, advancements in pharmacotherapy include medications that target appetite-regulating hormones, supporting sustainable weight loss. Bariatric medicine now emphasizes personalized treatment plans, considering each patient's genetic, hormonal, and metabolic profiles. These innovations not only promote weight loss but also improve conditions like type 2 diabetes and hypertension, significantly enhancing quality of life.