As the use of anti-obesity medications (AOMs) continues to grow, so does the need to adopt fitness strategies that complement their benefits while addressing the unique challenges faced by individuals on these treatments. This presentation focuses on breaking traditional exercise [....] » Read More
Atrial fibrillation (AF) is the most common cardiac arrhythmia, and its prevalence is significantly higher in individuals with obesity. This association is driven by multiple interrelated pathophysiological mechanisms, including structural, electrical, and metabolic changes in th [....] » Read More
Obesity poses a significant threat to the health and safety of first responders. It increases the risk of job- related disabilities and various illnesses such as neurovascular, cardiovascular, endocrine, and oncologic diseases. It is a primary contributor to sudden cardiac events [....] » Read More
Emotional eating is an increasingly prevalent behavioral pattern characterized by the consumption of food in response to emotional states rather than physiological hunger. It contributes significantly to challenges in weight regulation, mood disorders, and disordered eating patte [....] » Read More
Weight loss, whether achieved through caloric restriction or pharmacological therapy with glucagon-like peptide-1 receptor agonists (GLP-1 RAs), is effective in reducing obesity and improving cardiometabolic health. However, a significant portion of this weight loss often comes a [....] » Read More
Obesity is a major risk factor for the development and progression of heart failure (HF). It is present in approximately 70% of patients with heart failure with preserved ejection fraction (HFpEF) when assessed using body mass index (BMI), with an even higher prevalence when eval [....] » Read More
The unprecedented weight loss efficacy of GLP-1-based therapies has fueled a rapidly proliferating market for GLP-1-based obesity treatments and spurred increased drug development for new weight loss agents with potential competitive advantages over existing therapies. We analyze [....] » Read More
Clinical development pipeline in weight management is expected to grow by 11/12% YoY (Year-on-Year) with more than 120 drugs at different stages of clinical development and a 64% PTSR1 (Phase Transition Success Rate) from phase II to III. Moreover, we expect that the number of pa [....] » Read More
Clinical development pipeline in weight management is expected to grow by 11/12% YoY (Year-on-Year) with more than 120 drugs at different stages of clinical development and a 64% PTSR1 (Phase Transition Success Rate) from phase II to III. Moreover, we expect that the number of pa [....] » Read More
With the increasing utilization of glucagon-like peptide-1 receptor agonists (GLP-1 RAs) as a therapeutic strategy for obesity management, there is a critical need for coordinated nutrition guidance to enhance the efficacy and safety of these medications. GLP-1 RAs are effec [....] » Read More
Dietary fiber has a number of other physiologically beneficial effects interrelated to reduce the risk of cancer and heart disease. (Barry V. and Leon P., 2001). Extensive epidemiologic evidence supports the theory that dietary fiber may protect against large bowel cancer. Correl [....] » Read More
Maternal obesity is a well-established risk factor for gestational diabetes mellitus (GDM), a condition defined by glucose intolerance with onset during pregnancy. A central mechanism underlying this association involves dysfunction of white adipose tissue (WAT), an endocrine org [....] » Read More
Introduction: Practical trial highlights the gut microbiota’s role in modulating systemic inflammation, influencing nutrient availability, and immune function, which directly enhances muscle injury recovery and play a critical role in tissues repair and overall rehabilitati [....] » Read More
Background and Objective: Quality of life in severe obesity may be affected by gastrointestinal symptoms such as reflux, bloating, dyspepsia, stomach pain, and altered bowel patterns. Curcumin, bioactive compound found in turmeric (Curcuma longa L.), possess anti-inflammatory and [....] » Read More
The obesity epidemic is not just a public health crisis — it is a battle between medicine and marketing, where billion-dollar industries exploit neuroscience to override biology. While doctors work to treat obesity with medical interventions, food marketers weaponize neurom [....] » Read More
The obesity epidemic is not solely a matter of biology or behavior—it is a high-stakes psychological battleground where food companies use neuromarketing to hijack the brain's reward system. In this provocative and interactive 90-minute workshop, Michelle Petties— [....] » Read More
Dr. Colleen Lindsey loves helping people improve their lives. Using her 150-pound weight-loss journey to catapult further change in her own life, she has identified six steps necessary for change to occur for people. Change happens when people understand themselves, adjust min [....] » Read More
Suizan's Story: From Accidental Healthy Mom to Empowered Advocate Born 9 pounds 9 ounces, my struggle with weight started on day one—and it didn’t get easier. I filled my plate like it was my last meal, inquired about dinner while eating lunch, and grew up hear [....] » Read More
Objective: Obesity is a rising global health concern. Research on the long-term effectiveness of integrating intensive lifestyle modification (ILM) and meal replacement (MR) interventions for obesity management, particularly over extended periods is limited. This study evaluated [....] » Read More
The study aimed to produce a functional soft cheese with garlic extract (GE). First, the GE was encapsulated using gum Arabic (GA) and whey protein isolate, and its characteristics [zeta-potential, particle size, Coacervates yield, Encapsulation efficiency and polydispersity inde [....] » Read More
Background: The plasticity of human body in terms of surface area and composition is a challenge for health care units to address obesity. What they need is a cost-effective, easy to use tool to manage the daily clinical settings. For that reason, Dahlmann created a model that re [....] » Read More
Obesity is an epidemic in America, proportionally way higher than the rest of the world. Three out of four Americans are overweight including obese. The focus of the talk is to discuss this preventable chronic disease by addressing the physical, psychological and spiritual [....] » Read More
Background: A hiatal hernia occurs when abdominal contents protrude into the mediastinum via the diaphragmatic hiatus, often due to weakened phreno-esophageal ligaments. Diagnosis involves clinical assessment, imaging, and endoscopy. Management varies from lifestyle changes to su [....] » Read More
Background: Omega loop gastric bypass (OLGB) has been viewed with skepticism after the failure of the Bold Mason loop.^ During the past 15 years, a growing number of authors worldwide approved that OLGB is a safe and effective procedure, which appears clearly from the operative o [....] » Read More
Autism Spectrum Disorder (ASD) is a neurodevelopmental condition characterized by challenges in social communication, restricted interests, and repetitive behaviors. Children with ASD are at increased risk for various health-related challenges, including gastrointestinal issues, [....] » Read More
Background: Obesity and overweight remain pressing public health challenges, closely linked to chronic conditions such as cardiovascular disease, type 2 diabetes, and hypertension. Despite well-established health consequences, sustainable and effective weight loss interventions, [....] » Read More
Gastric remnant volvulus after Roux-en-Y Gastric Bypass (RYGB) is an exceptionally rare complication, with only a few reported cases in the literature. This presentation will discuss the first documented case of gastric remnant volvulus in a patient who previously underwent sleev [....] » Read More
Rationale: Bariatric surgery is a common surgical intervention for the treatment of severe obesity. Declines in respiratory function, muscle mass, and strength are very common in obese adults and are strongly associated with frailty, physical disability, and mortality. Multimodal [....] » Read More
Alterations in the composition of the gut microbiota are associated with several diseases. The use of antibiotics has been a strategy to study the impact of the gut microbiota on the host. The aim of the study was to evaluate the effect of antibiotic treatment on the metabolism o [....] » Read More
Introduction: The long-term effectiveness of different bariatric procedures remains an area of active investigation. This study aims to compare the long-term outcomes of Laparoscopic Sleeve Gastrectomy (LSG), Roux-en-Y Gastric Bypass (RYGB), and One-Anastomosis Gastric Bypass (OA [....] » Read More
Background: Non-alcoholic steatohepatitis (NASH), recently redefined as metabolic dysfunction-associated steatohepatitis (MASLD/MASH), is a progressive fatty liver disease with high unmet medical need. Incretin-based multi-agonists, which combine GLP-1 with GIP and/or glucagon re [....] » Read More
Introduction: GLP-1 medications are taking the market by a storm. Despite their popularity, concerns remain about the short and long-term safety of GLP-1 medications in different patient populations. Here, we compare the safety and efficacy of GLP-1 medications to non-GLP-1 medic [....] » Read More
Aims: This study aims to investigate the incidence rate and risk factors for hypoglycemia among individuals with type 1 (T1DM) and type 2 diabetes (T2DM) in Saudi Arabia receiving insulin treatment. Methods: A cross-sectional study was conducted at Prince Mohammed bin Abdulaziz N [....] » Read More
Background: Overweight and obesity are rising rapidly in preschool children.Obesity is apredisposing factor of many diseases.Overweight and obesity can affect the quality of life of children and reduce it. Overweight in childhood is a significant predictor of obesity in adulthood [....] » Read More
Disruptions of biological processes operating within adipose tissue can disturb healthy systemic physiology and develop metabolic diseases such as obesity and type 2 diabetes. Uncovering the biomolecular processes regulating adipocyte functionality can be the key to mitigating me [....] » Read More
The heart and brain are interconnected and risk factors that impact the heart can negatively affect the brain and cognition. Among the underlying features that foster both poor brain health and poor heart health are obesity, diabetes, physical inactivity and low sleep quality. Ob [....] » Read More
The heart and brain are interconnected and risk factors that impact the heart can negatively affect the brain and cognition. Among the underlying features that foster both poor brain health and poor heart health are obesity, diabetes, physical inactivity and low sleep quality. Ob [....] » Read More
While new medications like GLP-1s offer rapid results for weight loss and diabetes management, they do not address the systemic, cultural, and behavioural drivers behind the crisis. Childhood obesity and type 2 diabetes continue to rise - even as awareness, access to treatment, a [....] » Read More
In today’s fast-paced professional environment, workplace productivity is significantly impacted by metabolic health, weight management, and chronic disease. This presentation explores how personalized treatments, particularly GLP-1 receptor agonist (GLP-1RA) medications, h [....] » Read More
Introduction: The rising interest in obesity treatment has led to widespread use of diabetes medications—such as Liraglutide, Ozempic, Metformin, and Mounjaro—for weight loss. While these drugs show promise, many clinical trials studying them remain unpublished or dis [....] » Read More
Genetics is the study of genes and heredity. Genetics factor are inheritance transferable from parents to the offering, protein sequence, DNA component and genetic materials Heredity is also the passing of genetic information and traits such as eye colour, behaviour, height, weig [....] » Read More
This inspiring case study celebrates the powerful stories of women who have transformed their lives by embracing a holistic approach to obesity management. Through a supportive, women-centered community, these individuals combined consistent movement, activity and exercise, reali [....] » Read More
This inspiring case study celebrates the powerful stories of women who have transformed their lives by embracing a holistic approach to obesity management. Through a supportive, women-centered community, these individuals combined consistent movement, activity and exercise, reali [....] » Read More
Problem/Situation: In 2021, a review of our waitlist population indicated that 18% of our patients had a BMI > 35, putting them at a higher risk of cardiovascular events post-transplant. 2% had a BMI > 40, making them ineligible for transplant. If these patients took part i [....] » Read More
Glucagon-like peptide-1 (GLP-1) receptor agonists have revolutionized obesity management, demonstrating significant efficacy in weight reduction and glycemic control. While these medications facilitate weight loss primarily through appetite suppression and delayed gastric emptyin [....] » Read More
Introduction: In Germany, 14% of girls and 8% of boys from 3-6 years are overweight or obese. These rates have become worse due to the Covid 19 pandemic. Being overweight in early childhood often continues into adolescence and adulthood, and can result in a physical and psycholog [....] » Read More
Fibrosis refers to the excessive accumulation of extracellular matrix, which is associated with metabolic dysfunction in white adipose tissue (WAT) in obesity. Factors such as energy imbalance and hepatic steatosis are related to the development and progression of this conditio [....] » Read More
Exercise provides significant health benefits by enhancing immune system function, supporting balanced immune responses, and contributing to overall health and quality of life. This study aimed to investigate the differences in immune response to the acute effects of high-intensi [....] » Read More
Introduction: Epicardial fat covers about 80% of the heart surface. It is located along the coronary arteries, above the right ventricle, especially along the right border, anterior surface and at the apex. Three quarters of all epicardial fat (EF) is located on the surface of th [....] » Read More
Weight loss is not just about physical changes in the body; it also requires psychological and behavioral transformations. Psychological factors play a crucial role in initiating, maintaining, and improving the process of weight loss. This article explores the impact of psycholog [....] » Read More
While GLP-1 agonists demonstrate efficacy in trials, real-world discontinuation exceeds 50% at 6 months - a statistic reflecting the limitations of medication-only approaches. Our Great Toronto Area (GTA)- based clinics’ multidisciplinary model (integrating CBT, body compos [....] » Read More
Background: Weight Management Medications (WMMs) demonstrate significant benefits including weight loss and improvement in cardiovascular risk factors (blood pressure, lipid profile, HbA1c levels, inflammation), while behaviorally reducing food cravings, "food noise", a [....] » Read More
While numerous obesity-focused programs exist, limited research addresses the unique needs of perimenopausal and postmenopausal women, who often experience weight gain alongside other symptoms. Traditional interventions, such as intensive exercise or restrictive diets, may be uns [....] » Read More
Background: An important determinant of the profession of a soldier is maintaining a high level of physical fitness, which is periodically tested in the army. In order to maintain high physical fitness, one should regularly undertake physical activity of varying intensity, both d [....] » Read More
Background & Aims: Obesity remains a major public health concern in Portugal. Hypocaloric diets with reduced carbohydrate content have shown promise in promoting weight loss and improving metabolic health, but long-term adherence remains a challenge. This study aimed to evalu [....] » Read More
Everyone generally admits that nutrition is a key health factor. However, there are many obstacles to translating this recognition into healthy eating habits. Proof of this is the high prevalence of chronic non-communicable diseases, such as cardiovascular diseases, diabetes, or [....] » Read More
Periodontitis is a multifactorial chronic inflammatory disease associated with bacterial biofilm and progressive destruction of the tooth-supporting tissues. Recent evidence has linked periodontitis to systemic conditions such as obesity, in which pro- inflammatory markers like i [....] » Read More
Obesity is one of the most pressing health challenges of the 21st century, contributing to diabetes, cardiovascular disease, and reduced quality of life. Traditional approaches such as diet, exercise, and behavioral modification, while essential, often yield limited long-term suc [....] » Read More
This literature review focuses on patients with congenital leptin deficiency who had never been exposed to endogenous or exogenous leptin and its ef [....] » Read More
Life in the frontline zone is characterized by daily multiple negative effects of extreme situations on humans. Social stressors associated with living conditions in frontline zones, such as sirens sounding around the clock, the threat to life at any time due to attacks and explo [....] » Read More
When the American Academy of Pediatrics published the new clinical guidelines for evaluation and treatment of pediatric obesity in 2023 it placed an emphasis on using pharmacotherapy early in the care of patients. This has required a cultural shift in the practice of pediatrics. [....] » Read More
Introduction: A recent clinical debrief at the GP practice identified that several patients with a history of bariatric surgery were not receiving follow-up care in accordance with BOMSS guidelines, with adverse effects on health outcomes. A review of patient records was undertak [....] » Read More
Introduction: Metabolic Syndrome (MetS), characterized by a cluster of conditions such as obesity, hypertension, insulin resistance, and dyslipidemia, has been increasingly linked to cardiovascular complications. While its association with heart disease is well known, its specifi [....] » Read More
Background: The aim of the present study was to assess the effects of a hyperlipidic diet set before puberty in male Wistar rats’ gonadal weights and testicular functions. Methods: Males rats were used for the study, they were randomly distributed into 2 groups: Control [....] » Read More
Purpose: Obesity and poor sleep quality are interconnected health concerns with complex, multifactorial origins. While physiological pathways contribute to this two-way relationship, growing evidence highlights the role of social and behavioral factors in shaping this associati [....] » Read More
While GLP-1 agonists demonstrate efficacy in trials, real-world discontinuation exceeds 50% at 6 months - a statistic re?ecting the limitations of medication-only approaches. Our Great Toronto Area (GTA)- based clinics’ multidisciplinary model (integrating CBT, body composi [....] » Read More
This study evaluated the efficacy of an AI-guided dietary supplement regimen compared to a standard physician-guided regimen in managing Type 2 diabetes (T2D). A total of 160 patients were randomly assigned to either the AI-guided group (n=80) or the physician-guided group (n=80) [....] » Read More
Bariatric and metabolic surgery has proven to be an effective intervention for achieving rapid weight loss in individuals with severe obesity. While these surgeries can lead to significant health improvements, for some patients, they may experience psycho-behavioral challenges in [....] » Read More
In 2022, worldwide 2.5 billion people over the age of 18 were considered overweight and 890 million of them were considered obese (World Health Organization [WHO], 2024). To determine these diagnoses, a body mass index (BMI) must be obtained. BMI is calculated by obtaining a pers [....] » Read More
Background: Lipodystrophy is a rare and complex condition characterized by abnormal fat distribution and severe metabolic complications, significantly impacting the quality of life of affected individuals. To better understand the experiences of patients. Lipodystrophy United, a [....] » Read More
Obesity is a global public health problem, associated with various metabolic comorbidities. Among its pathophysiological characteristics, the accumulation of white adipose tissue (WAT) stands out. In addition, it is widely recognized that the WAT plays an important endocrine ro [....] » Read More
Obesity is a complex, multifactorial chronic disease that poses significant health risks. Recent advancements in artificial intelligence (AI) offer the potential for more personalized and effective dietary supplement (DS) regimens to promote weight loss. This study aimed to evalu [....] » Read More
Background: In patients preparing for bariatric surgery, the compulsive consumption of palatable and hyperpalatable food may interfere with successful postoperative weight loss, increase the risk of psychological and behavioral complications, and might influence body image percep [....] » Read More
Background: In 2021 28% of Australian mothers were overweight and 23% were obese. Women who are overweight and obese are more likely to gain excessive weight in pregnancy. Up to one third of Australian women had gained excessive weight by 22 weeks gestation. Excessive gestational [....] » Read More
Introduction: GLP-1 receptor agonists (GLP-1 RAs) such as semaglutide have demonstrated impressive efficacy in inducing weight loss and improving metabolic health. However, recent reviews suggest that approximately 45% of the total weight loss under semaglutide may derive from fa [....] » Read More
Lead (Pb) is considered an endocrine threat that interferes with hormonal regulation. Body mass index is a leading indicator of general obesity. Waist circumference, an indicator of central obesity, is considered the primary determinant of cardiovascular incidence and one of the [....] » Read More
Background: Evidence on the associations between iron status biomarkers and both overweight/obesity prevalence and body mass index (BMI) is limited. Methods: This cross-sectional analysis utilized data from 5454 participants in the NHANES 2003-2006 and 2017-2020 cycles. Overw [....] » Read More
Objective: The study aims to help identify barriers that cause patients to cancel their bariatric surgery in the patient population of Kings County Medical Center in East Flatbush, New York. Methods: 72 patients that canceled their bariatric surgery procedure, were called to p [....] » Read More
Background: Glucagon-like peptide-1 (GLP-1) receptor agonists are seen as a first-line treatment for Type II Diabetes Mellitus (T2DM).1 However, multiple recent randomized controlled trials have shown that GLP-1 agonists are also effective for weight loss and metabolic control.2 [....] » Read More
Title : Proposed shorter duration protocols for measuring exercise energetics utilizing whole room indirect calorimetry
Russell Rising, D & S Consulting Services Inc, United States
Background: Previously, 60 minutes was the shortest testing duration that was validated for measurement of exercise energetics (EXEE; kcal) utilizing whole room indirect calorimetry (WRIC). This comprised of 15, 30 and 15 minutes for warmup/stretching, steady state exercise and c [....] » Read More
Title : Empowering successful outcomes programming support strategies for customers on antiobesity medications 2025 programming updates
Bob Esquerre, Esquerre Fitness Group International, United States
In 2013, the American Medical Association officially recognized Obesity as a disease. By 2030, clinically defined obesity is projected to affect over one billion people globally, representing a significant public health crisis. Defined by a body mass index (BMI) of 30 or higher, [....] » Read More
Title : Exploring the impact of MC4R gene variants on food preferences
Jeane Silva, Augusta University, United States
Obesity is a significant risk factor for life-threatening diseases that increase morbidity and mortality rates. Currently, obesity is a worldwide epidemic, and the prevalence of obesity has been rising at unprecedented levels. The obesity rate among adults aged 20 and older is 40 [....] » Read More
Title : Transgenerational inheritance of obesity caused by epigenetic factors
Hassan Massoud Heshmati, Endocrinology Metabolism Consulting, LLC, Hassan Heshmati and Valerie Shaw Endocrine Research, United States
Obesity is defined as a state of excess body fat responsible for increased body weight. It is a major health problem in several countries causing increased morbidity and mortality and high cost for the society. Obesity is a complex multifactorial disease with genetic and non-gene [....] » Read More
Title : Nutrition + gentle strength: Preventing sarcopenia for a vibrant life
Benjamin Sley, Texas Bar Association Member, U.S. Marine Corps Veteran, United States
Benjamin Sley is a Marine Corps veteran, chemist, certified nutritionist, and nationally recognized expert on permanent weight loss without injections or extreme exercise. After personally losing over 75 pounds and keeping it off for more than six years, Ben now helps others&mdas [....] » Read More
Title : How to align stakeholders and accelerate obesity outcomes by enabling buy-in
Charles Bernard, Criteria for Success, Inc., United States
Many of the most promising obesity initiatives struggle not because of clinical shortcomings, but because key stakeholders fail to commit. Patients drop out Programs lose momentum Funders hesitate. Internal teams misalign. These are not just operational issues. T [....] » Read More
Title : Same day discharge metabolic and bariatric surgery: Experience of a bariatric tertiary center
Ronald Denis, Sacred Heart Hospital of Montréal, Canada
Since the event of minimally invasive surgery, bariatric surgery has taken such a lead that, in Canada, lack of hospital beds, budgets and manpower has made us look at other issues in order to be able to operate our patients in a reasonable time. This study examines the feasibili [....] » Read More
Title : Why is obesity chronic and relapsing?
Jyoti Manekar, OMA, OAC, AAFP, ABFM, GAFP, AMA, United States
Obesity, often misunderstood as a simple lifestyle issue, is a complex, chronic, and relapsing condition influenced by a combination of physiological, psychological, and environmental factors. Despite advancements in diets, pharmacological treatments, and surgical interventions, [....] » Read More
Title : Unlock the power of nutrition: Weight loss in the era of medications
Kelly Springer, Kelly's Choice, United States
With the rapid rise in GLP-1 medications like Ozempic® and Wegovy®, the landscape of weight loss is changing. While these medications offer powerful short-term results, nutrition remains the cornerstone of long-term success. In this session, Registered Dietitian Kelly Spr [....] » Read More
Title : Single Anastomosis Sleeve Ileal Bypass(SASI) as a second stage after Sleeve Gastrectomy (SG) – A unicentric experience from a Canadian tertiary bariatric center
Studer Anne Sophie, Sacred-Heart Hospital of Montreal, Canada
Background: Single-anastomosis sleeve-ileal bypass (SASI) is a 2nd-stage surgical option for initial suboptimal clinical response or recurrence of obesity after sleeve gastrectomy (SG). It is an emerging and interesting option, as it combines several mechanisms such as dietary re [....] » Read More
Title : Understanding and addressing the multifactorial nature of obesity: A comprehensive approach
Christina Campbell, Michigan State University, United States
Obesity is a complex, multifactorial condition influenced by an intricate interplay of dietary, lifestyle, genetic, and epigenetic factors. Effective weight management necessitates a deeper understanding of these root causes to develop targeted interventions that promote sustaina [....] » Read More
Title : Physiology of the anti-calorie diet
Auston Cherbonneaux, Freelance, United States
There has been a misconception about energy in nutrition, exercise, and biological sciences, and that misconception is that we operate on the same thermodynamics as a combustion engine. This is the premise of the calorie measurement, and in this presentation I will discuss the th [....] » Read More
Title : Practicing advanced applications in modern nutrition and exercise science
Auston Cherbonneaux, Freelance, United States
With the knowledge that there is no combustion in the cell for energy production, and that all nutrients supply the body with energy, participants will now be ready to analyze applications, models, and methods for weight loss and weight management with a modern understanding [....] » Read More