Abstract:
Obesity is a complex chronic disease that exerts profound and interconnected effects on cardiovascular, kidney, and metabolic health. Yet most global care models continue to prioritize weight change alone while overlooking the multisystem nature of obesity-related organ dysfunction. This gap contributes to underdiagnosis of early CKM disease, delayed initiation of protective therapies, and persistent disparities across diverse populations. This presentation outlines a practical, integrated care framework that unifies cardiovascular, kidney, and metabolic principles into routine obesity management. Drawing on multidisciplinary guidelines, global epidemiologic trends, and real-world experience across hospital medicine, nephrology, obesity medicine, and nutrition, the session highlights how coordinated treatment pathways—incorporating pharmacotherapy, metabolic monitoring, renal and cardiovascular surveillance, and targeted lifestyle intervention—can simultaneously reduce cardiometabolic risk and organ decline. Special emphasis will be placed on operationalizing the emerging Cardiovascular–Kidney–Metabolic (CKM) model in clinical practice, clarifying key patient phenotypes, and identifying high-yield strategies applicable in both high-resource and low-resource settings worldwide. By shifting the focus from weight loss alone to comprehensive multisystem disease modification, this approach offers a scalable roadmap capable of improving outcomes, reducing global disease burden, and enhancing long-term prevention. Attendees will gain actionable tools for implementing CKM-aligned obesity care in diverse clinical environments, with direct relevance to international health systems, primary care networks, and specialty practices.
Keywords: Obesity, CKM Syndrome, Cardiometabolic Health, Kidney Disease, Global Health, Metabolic Dysfunction, Integrated Care
